File:3k2p hiv rnaseH 2rn2 ecoli.png

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Summary

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English: The ribonuclease H domain from the HIV-1 reverse transcriptase protein (blue), with the four active-site carboxylate residues shown in magenta. The domain is superposed on the ribonuclease HI domain from Escherichia coli (tan).

Rendered from PDB 3K2P (HIV) and 2RN2 (E. coli).

Structure of HIV-1 reverse transcriptase with the inhibitor beta-Thujaplicinol bound at the RNase H active site.

Himmel, D.M., Maegley, K.A., Pauly, T.A., Bauman, J.D., Das, K., Dharia, C., Clark, A.D., Ryan, K., Hickey, M.J., Love, R.A., Hughes, S.H., Bergqvist, S., Arnold, E.

(2009) Structure 17: 1625-1635

PubMed: 20004166 PubMedCentral: PMC3365588 DOI: 10.1016/j.str.2009.09.016

Structural details of ribonuclease H from Escherichia coli as refined to an atomic resolution.

Katayanagi, K., Miyagawa, M., Matsushima, M., Ishikawa, M., Kanaya, S., Nakamura, H., Ikehara, M., Matsuzaki, T., Morikawa, K.

(1992) J.Mol.Biol. 223: 1029-1052

PubMed: 1311386
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Author Opabinia regalis

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