File:Ascorbate ferrireductase (transmembrane).svg

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Summary

Description
English: Ascorbate ferrireductase (transmembrane) (EC 1.16.5.1) is an enzyme with system name Fe(III):ascorbate oxidorectuctase (electron-translocating). This enzyme catalyses the transference of an electron from ascorbate to the ferric ion. The overall reaction is as follows:
ascorbate[in] + Fe(III)[out] monodehydroascorbate radical[in] + H+[in] + Fe(II)[out]
 
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References

  • Flatmark, T. and Terland, O. (1971). "Cytochrome b561 of the bovine adrenal chromaffin granules. A high potential b-type cytochrome". Biochim. Biophys. Acta 253 (2): 487–491. DOI:10.1016/0005-2728(71)90052-1. PMID 4332308.
  • McKie, A.T., Barrow, D., Latunde-Dada, G.O., Rolfs, A., Sager, G., Mudaly, E., Mudaly, M., Richardson, C., Barlow, D., Bomford, A., Peters, T.J., Raja, K.B., Shirali, S., Hediger, M.A., Farzaneh, F. and Simpson, R.J. (2001). "An iron-regulated ferric reductase associated with the absorption of dietary iron". Science 291 (5509): 1755–1759. DOI:10.1126/science.1057206. PMID 11230685.
  • Wyman, S., Simpson, R.J., McKie, A.T. and Sharp, P.A. (2008). "Dcytb (Cybrd1) functions as both a ferric and a cupric reductase in vitro". FEBS Lett. 582 (13): 1901–1906. DOI:10.1016/j.febslet.2008.05.010. PMID 18498772.
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