(3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase

(3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase (, DpgC) is an enzyme catalyses the following chemical reaction


 * (3,5-dihydroxyphenyl)acetyl-CoA + O$2$ 2-(3,5-dihydroxyphenyl)-2-oxoacetate + CoA.

This enzyme is involved in the biosynthesis of the nonproteinogenic amino acid (S)-3,5-dihydroxyphenylglycine (Dpg) responsible of the production of vancomycin and teicoplanin antibiotics. It catalyzes the unusual conversion 3,5-dihydroxyphenylacetyl-CoA (DPA-CoA) to 3,5-dihydroxyphenylglyoxylate.