(R)-4-hydroxyphenyllactate dehydrogenase

(R)-4-hydroxyphenyllactate dehydrogenase is an enzyme that catalyzes a chemical reaction


 * (R)-3-(4-hydroxyphenyl)lactate + NAD(P)+ $$\rightleftharpoons$$ 3-(4-hydroxyphenyl)pyruvate + NAD(P)H + H$+$

The 3 substrates of this enzyme are (R)-3-(4-hydroxyphenyl)lactate, NAD$+$, and NADP$+$, whereas its 4 products are 3-(4-hydroxyphenyl)pyruvate, NADH, NADPH, and H$+$.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD$+$ or NADP$+$ as acceptor. The systematic name of this enzyme class is (R)-3-(4-hydroxyphenyl)lactate:NAD(P)$+$ 2-oxidoreductase. Other names in common use include (R)-aromatic lactate dehydrogenase, and D-hydrogenase, D-aryllactate. This enzyme participates in tyrosine and phenylalanine catabolism.