(R)-citramalate synthase

(R)-citramalate synthase (, CimA) is an enzyme. This enzyme catalyses the following chemical reaction


 * acetyl-CoA + pyruvate + H2O $$\rightleftharpoons$$ CoA + (2R)-2-hydroxy-2-methylbutanedioate

This enzyme participates in a novel pyruvate pathway for isoleucine biosynthesis.