1749 in architecture

Buildings

 * April 12 – The Radcliffe Camera in Oxford, England, designed by James Gibbs, is opened as a library.
 * Mathematical Bridge at Queens' College, Cambridge, England, designed by William Etheridge, is built by James Essex.
 * La Vieille Charité almshouses in Marseille completed to the designs of Pierre Puget.
 * Work begins on King's Chapel, in Boston, Massachusetts, designed by Peter Harrison.
 * Work begins on Reales Astilleros de Esteiro in Ferrol, Spain.

Births

 * June 9 – Andreas Kirkerup, Danish architect (died 1810)
 * Louis Montoyer, Austrian Netherlands architect (died 1811)
 * Angelo Venturoli, Italian architect (died 1821)

Deaths

 * January 9 – Henry Herbert, 9th Earl of Pembroke, English courtier and architect (born 1693)
 * January 31 – Roger Morris, English architect (born 1695)