1909–10 Iowa State Cyclones men's basketball team

The 1909–10 Iowa State Cyclones men's basketball team (also known informally as Ames) represented Iowa State University during the 1909-10 NCAA College men's basketball season. The Cyclones were coached by Clyde Williams, in his third season with the Cyclones. The Cyclones played their home games at the Margaret Hall Gymnasium in Ames, Iowa.

They finished the season 9–7, 6–2 in Missouri Valley play to finish in second place in the North division.

Schedule and results
!colspan=6 style=""|Regular Season