1910 Holy Cross football team

The 1910 Holy Cross football team was an American football team that represented the College of the Holy Cross in the 1910 college football season.

In its fourth year under head coach Timothy F. Larkin, the team compiled a 3–3–2 record. John C. Lawlor was the team captain.

Holy Cross played its home games at Fitton Field on the college campus in Worcester, Massachusetts.