1910 Sewanee Tigers football team

The 1910 Sewanee Tigers football team represented Sewanee: The University of the South during the 1910 college football season as a member of the Southern Intercollegiate Athletic Association (SIAA). The Tigers were led by head coach Harris G. Cope in his second season and finished with a record of eight wins and two losses (8–2 overall, 3–1 in the SIAA).