1921 Columbia Lions football team

The 1921 Columbia Lions football team was an American football team that represented Columbia University as an independent during the 1918 college football season. In his second season, head coach Frank "Buck" O'Neill led the team to a 2–6 record, with the Lions outscored 148 to 82 by opponents.

The team played most of its home games on South Field, part of the university's campus in Morningside Heights in Upper Manhattan.