1922 Sewanee Tigers football team

The 1922 Sewanee Tigers football team represented Sewanee: The University of the South during the 1922 college football season as a member of the Southern Intercollegiate Athletic Association (SIAA). The Tigers were led by head coach John Nicholson in his second season and finished with a record of three wins, four losses, and one tie (3–4–1 overall, 1–1 in the SIAA).