1923 Iowa State Cyclones football team

The 1923 Iowa State Cyclones football team represented Iowa State College of Agricultural and Mechanic Arts (later renamed Iowa State University) in the Missouri Valley Conference during the 1923 college football season. In their second season under head coach Sam Willaman, the Cyclones compiled a 4–3–1 record (3–2–1 against conference opponents), finished in fourth place in the conference, and outscored opponents by a combined total of 121 to 93. They played their home games at State Field in Ames, Iowa. Ira Young was the team captain.

On October 8, two days after the Minnesota game, tackle Jack Trice died due to hemorrhaged lungs and internal bleeding stemming from injuries he sustained during the game.