1938 Cal Poly Mustangs football team

The 1938 Cal Poly Mustangs football team represented California Polytechnic School—now known as California Polytechnic State University, San Luis Obispo—as an independent during the 1938 college football season. Led by sixth-year head coach Howie O'Daniels, Cal Poly compiled a record of 7–2. The team outscored its opponents 119 to 53 for the season. The Mustangs played home games at Mustang Stadium in San Luis Obispo, California.

Cal Poly was a two-year school until 1941 and competed as an independent from 1929 to 1945.