1941 Xavier Musketeers football team

The 1941 Xavier Musketeers football team was an American football team that represented Xavier University as an independent during the 1941 college football season. In its seventh season under head coach Clem Crowe, the team compiled a 9–1 record and outscored opponents by a total of 257 to 47.

Xavier was ranked at No. 52 (out of 681 teams) in the final rankings under the Litkenhous Difference by Score System for 1941.

The team played its home games at Xavier Stadium in Cincinnati. Halfback Chet Mutryn starred on offense for Xavier.