1942 South Carolina Gamecocks football team

The 1942 South Carolina Gamecocks football team was an American football team that represented the University of South Carolina as a member of the Southern Conference during the 1942 college football season. In their fifth season under head coach Rex Enright, the Gamecocks compiled an overall record of 1–7–1 with a mark of 1–4 in conference play, placing 14th in the SoCon. The team's only victory was over The Citadel.

South Carolina was ranked at No. 81 (out of 590 college and military teams) in the final rankings under the Litkenhous Difference by Score System for 1942.