1943 Denver Pioneers football team

The 1943 Denver Pioneers football team was an American football team that represented the University of Denver as member of the Mountain States Conference during the 1943 college football season. In their first and only season under head coach Mark Duncan, the Pioneers compiled a 2–5 record and were outscored by a total of 186 to 70.

In the final Litkenhous Ratings, Denver ranked 129th among the nation's college and service teams with a rating of 58.0.