1943 Penn Quakers football team

The 1943 Penn Quakers football team was an American football team that represented the University of Pennsylvania as an independent during the 1943 college football season. In its sixth season under head coach George Munger, the team compiled a 6–2–1 record, was ranked No. 20 in the final AP Poll, and outscored opponents by a total of 247 to 88 points.

In the final Litkenhous Ratings, Penn ranked 19th among the nation's college and service teams with a rating of 97.0.

The team played its home games at Franklin Field in Philadelphia.