1943 Penn State Nittany Lions football team

The 1943 Penn State Nittany Lions football team represented the Pennsylvania State University in the 1943 college football season. The team was coached by Bob Higgins and played its home games in New Beaver Field in State College, Pennsylvania.

In the final Litkenhous Ratings, Penn State ranked 58th among the nation's college and service teams with a rating of 81.7.