1943 Rice Owls football team

The 1943 Rice Owls football team was an American football team that represented Rice University as a member of the Southwest Conference (SWC) during the 1943 college football season. In its fourth season under head coach Jess Neely, the team compiled a 3–7 record (2–3 against SWC opponents) and was outscored by a total of 183 to 60.

In the final Litkenhous Ratings, Rice ranked 90th among the nation's college and service teams with a rating of 68.6.