1943 USC Trojans football team

The 1943 USC Trojans football team represented the University of Southern California (USC) in the 1943 college football season. In their second year under head coach Jeff Cravath, the Trojans compiled an 8–2 record (5–0 against conference opponents), won the Pacific Coast Conference championship, defeated Washington in the 1944 Rose Bowl, and outscored their opponents by a combined total of 155 to 58.

In the final Litkenhous Ratings, USC ranked 45th among the nation's college and service teams with a rating of 84.8.