1943 VMI Keydets football team

The 1943 VMI Keydets football team was an American football team that represented the Virginia Military Institute (VMI) during the 1943 college football season as a member of the Southern Conference. In their seventh year under head coach Pooley Hubert, the team compiled an overall record of 2–6.

In the final Litkenhous Ratings, VMI ranked 180th among the nation's college and service teams with a rating of 44.5.