1946 Iowa State Teachers Panthers football team

The 1946 Iowa State Teachers Panthers football team represented Iowa State Teachers College in the North Central Conference (NCC) during the 1946 college football season. In its ninth season under head coach Clyde Starbeck, the team compiled a 4–1–2 record (2–0–1 against NCC opponents), shut out it final four opponents, won the NCC championship, and outscored opponent by a total of 175 to 32.

Iowa Teachers ranked third nationally in total defense among small college teams, giving up an average of only 108.5 yards per game. The team was ranked at No. 85 in the final Litkenhous Difference by Score System rankings for 1946.

Five players were selected to the all-conference team: ends Nick Avelchas and Cy Bellock; halfbacks Pudge Camarata and Bob Williams; tackle Jason Loving; and guard Paul Salzman.