1948 Holy Cross Crusaders football team

The 1948 Holy Cross Crusaders football team was an American football team that represented the College of the Holy Cross as an independent during the 1948 college football season. In its first year under head coach Bill Osmanski, the team compiled a 5–5 record.

Holy Cross was ranked at No. 83 in the final Litkenhous Difference by Score System ratings for 1948.

The team played its home games at Fitton Field in Worcester, Massachusetts.