1952 Eastern Illinois Panthers football team

The 1952 Eastern Illinois Panthers football team represented Eastern Illinois State College (now known as Eastern Illinois University) as a member of the Interstate Intercollegiate Athletic Conference (IIAC) during the 1952 college football season. The team was led by sixth-year head coach Maynard O'Brien and played their home games at Lincoln Field in Charleston, Illinois. The Panthers finished the season with a 2–7 record overall and a 1–5 record in conference play, finishing last in the IIAC.