1961 Cal Poly Mustangs football team

The 1961 Cal Poly Mustangs football team represented California Polytechnic State College—now known as California Polytechnic State University, San Luis Obispo—as a member of the California Collegiate Athletic Association (CCAA) during the 1961 college football season. Led by LeRoy Hughes in his 12th and final season as head coach, Cal Poly compiled an overall record of 4–4 with a mark of 3–2 in conference play, placing second in the CCAA. The Mustangs played home games at Mustang Stadium in San Luis Obispo, California.