1965–66 Iowa State Cyclones men's basketball team

The 1965–66 Iowa State Cyclones men's basketball team represented Iowa State University during the 1965–66 NCAA Division I men's basketball season. The Cyclones were coached by Glen Anderson, who was in his seventh season with the Cyclones. They played their home games at the Iowa State Armory in Ames, Iowa.

They finished the season 11–14, 6–8 in Big Eight play to finish in a tie for fifth place.

Schedule and results
!colspan=6 style=""|Regular Season