1965 East Texas State Lions football team

The 1965 East Texas State Lions football team represented East Texas State University in the 1965 NAIA football season. They were led by Ernest Hawkins, who was in his second season. The Lions played their home games at Memorial Stadium and were members of the Lone Star Conference. The Lions finished the season with a 4–5 record.

All-Americans

 * Curtis Guyton, Third Team, running back

LSC First Team

 * John Jones, defensive tackle

LSC Honorable Mention

 * Jerry Jolley, defensive back
 * Wardell Richardson, defensive line