1966 Holy Cross Crusaders football team

The 1966 Holy Cross Crusaders football team was an American football team that represented the College of the Holy Cross as an independent during the 1966 NCAA University Division football season. Mel Massucco returned for his second year as head coach. The team compiled a record of 6–3–1.

All home games were played at Fitton Field on the Holy Cross campus in Worcester, Massachusetts.

Statistical leaders
Statistical leaders for the 1966 Crusaders included:
 * Rushing: Jack Lentz, 685 yards and 7 touchdowns on 177 attempts
 * Passing: Jack Lentz, 845 yards, 74 completions and 5 touchdowns on 153 attempts
 * Receiving: Pete Kimener, 409 yards and 2 touchdowns on 33 receptions
 * Scoring: Jack Lentz, 42 points from 7 touchdowns
 * Total offense: Jack Lentz, 1,530 yards (845 passing, 685 rushing)
 * All-purpose yards: Jack Lentz, 704 yards (685 rushing, 19 receiving)