1966 Oklahoma State Cowboys football team

The 1966 Oklahoma State Cowboys football team represented Oklahoma State University as a member of the Big Eight Conference during the 1966 NCAA University Division football season. Led by fourth-year head coach, the Cowboys compiled an overall record of 4–5–1 with a mark of 4–2–1, tying for third place in the Big 8. Oklahoma State played home game at Lewis Field in Stillwater, Oklahoma.

Oklahoma
Oklahoma State defensive backs Charlie Trimble and Willard Nahrgang stopped Oklahoma tailback Ron Shotts at the two on the conversion play to preserve their second straight win over the Sooners.

After the season
The 1967 NFL/AFL Draft was held on March 14–15, 1967. The following Cowboys were selected.