1966 Southern Illinois Salukis football team

The 1966 Southern Illinois Salukis football team was an American football team that represented Southern Illinois University (now known as Southern Illinois University Carbondale) as an independent during the 1966 NCAA College Division football season. Under first-year head coach Ellis Rainsberger, the team compiled a 4–5–1 record. The team played its home games at McAndrew Stadium in Carbondale, Illinois.