1969 Defiance Yellow Jackets football team

The 1969 Defiance Yellow Jackets football team was an American football team that represented Defiance College as a member of the Mid-Ohio Conference (MOC) during the 1969 NAIA football season. In their third year under head coach Roger Merb, the Yellow Jackets compiled a 9–0 record (3–0 against conference opponents), won the MOC championship, and outscored opponents by a total of 283 to 61.

At the end of the season, Merb was selected as the MOC bootball coach of the year. In addition, 14 Defiance players, including quarterback Jerry Griffith, were named to the 1969 MOC all-star team.

The 1969 season was one of three perfect seasons in Defiance football history, the others being in 1953 and 1966.