1969 Mississippi Valley State Delta Devils football team

The 1969 Mississippi Valley State Delta Devils football team represented Mississippi Valley State College (now known as Mississippi Valley State University) as a member of the Southwestern Athletic Conference (SWAC) during the 1969 NCAA College Division football season. Led by second-year head coach William Glosson, the Delta Devils compiled an overall record of 1–8, with a conference record of 1–6, and finished tied for seventh in the SWAC.