1973 Mississippi Valley State Delta Devils football team

The 1973 Mississippi Valley State Delta Devils football team represented Mississippi Valley State College (now known as Mississippi Valley State University) as a member of the Southwestern Athletic Conference (SWAC) during the 1973 NCAA Division II football season. Led by fourth-year head coach Davis Weathersby, the Delta Devils compiled an overall record of 3–5, with a conference record of 2–4, and finished sixth in the SWAC.