1978 American Airlines Tennis Games – Singles

Brian Gottfried was the defending champion but lost in the quarterfinals to Peter Fleming.

Roscoe Tanner won in the final 6–1, 7–6 against Raúl Ramirez.

Seeds

 * 1) 🇺🇸 Brian Gottfried (quarterfinals)
 * 2) 🇺🇸 Eddie Dibbs (second round)
 * 3) 🇪🇸 Manuel Orantes (quarterfinals)
 * 4) 🇲🇽 Raúl Ramirez (final)
 * 5)  Ilie Năstase (quarterfinals)
 * 6) 🇺🇸 Harold Solomon (third round)
 * 7) 🇺🇸 Sandy Mayer (first round)
 * 8) 🇺🇸 Roscoe Tanner (champion)
 * 9)  Jaime Fillol (third round)
 * 10) 🇦🇺 Phil Dent (first round)
 * 11) 🇺🇸 Stan Smith (third round)
 * 12) 🇦🇺 John Alexander (first round)
 * 13) 🇺🇸 Tim Gullikson (second round)
 * 14)  Cliff Drysdale (second round)
 * 15) 🇪🇸 José Higueras (second round)
 * 16) 🇦🇺 John Newcombe (first round)