1980–81 FA Vase

The 1980–81 FA Vase was the seventh season of the FA Vase, an annual football competition for teams in the lower reaches of the English football league system.

Whickham, of Tyne and Wear, won the competition, beating Willenhall Town in the final.

Semi-finals
Whickham won 2-1 on aggregate.

Willenhall Town won 3–1 on aggregate.