1980–81 Midland Football League

The 1980–81 Midland Football League was the 81st in the history of the Midland Football League, a football competition in England.

Premier Division
The Premier Division featured 17 clubs which competed in the previous season, along with one new club:
 * Guisborough Town, joined from the Northern Football Alliance

Division One
Division One featured 15 clubs which competed in the previous season, along with one new club:
 * Folk House Old Boys