1980 ABN World Tennis Tournament – Singles

Björn Borg was the defending champion of the singles event at the ABN World Tennis Tournament, but did not participate in this edition. Unseeded Heinz Günthardt won the title after a victory in the final against first-seeded Gene Mayer 6–2, 6–4.

Seeds
• #🇺🇸 Gene Mayer (final)

• #🇺🇸 John Sadri (quarterfinals)

• #🇺🇸 Stan Smith (first round)

• # Ivan Lendl (semifinals)

• #🇺🇸 Tim Gullikson (first round)

• #🇮🇹 Adriano Panatta (second round)

• #🇮🇳 Vijay Amritraj (quarterfinals)