1980 Birmingham Open – Singles

The 1980 Birmingham Open – Singles was an event of the 1980 Birmingham Open men's tennis tournament that was played in Birmingham, Alabama in the United States from January 14 through January 20, 1980. The draw comprised 32 players and 8 players were seeded. First-seeded Jimmy Connors was the defending singles champion and successfully defended his title, defeating Eliot Teltscher in the final, 6–3, 6–2.

Seeds
• # 🇺🇸 Jimmy Connors (champion)

• # 🇺🇸 Vitas Gerulaitis (quarterfinals)

• # N/A

• # N/A

• # 🇺🇸 Eddie Dibbs (quarterfinals)

• # 🇺🇸 Peter Fleming (semifinals)

• # 🇵🇱 Wojtek Fibak (second round)

• # 🇦🇷 José Luis Clerc (quarterfinals)