1980 French Open – Women's singles

Defending champion Chris Evert defeated Virginia Ruzici in the final, 6–0, 6–3 to win the women's singles tennis title at the 1980 French Open. It was her fourth French Open singles title and her tenth major singles title overall.

Seeds
The seeded players are listed below. Chris Evert is the champion; others show the round in which they were eliminated.


 * 1) 🇺🇸 Chris Evert (champion)
 * 2) 🇺🇸 Billie Jean King (quarterfinals)
 * 3) 🇦🇺 Wendy Turnbull (quarterfinals)
 * 4) 🇬🇧 Virginia Wade (third round)
 * 5) 🇦🇺 Dianne Fromholtz (semifinals)
 * 6) 🇺🇸 Kathy Jordan (quarterfinals)
 * 7)  Hana Mandlíková (semifinals)
 * 8) 🇷🇴 Virginia Ruzici (finalist)
 * 9)  Regina Maršíková (withdrew before the tournament began)
 * 10) 🇬🇧 Sue Barker (withdrew before the tournament began)
 * 11) 🇺🇸 Andrea Jaeger (first round)
 * 12)  Sylvia Hanika (third round)
 * 13) 🇺🇸 Caroline Stoll (second round)
 * 14)  Mima Jaušovec (third round)
 * 15) 🇺🇸 Kate Latham (first round)
 * 16)  Bettina Bunge (third round)

Key

 * Q = Qualifier
 * WC = Wild card
 * LL = Lucky loser
 * r = Retired