1980 Kilkenny Senior Hurling Championship

The 1980 Kilkenny Senior Hurling Championship was the 86th staging of the Kilkenny Senior Hurling Championship since its establishment by the Kilkenny County Board in 1887.

Ballyhale Shamrocks were the defending champions.

On 2 November 1980, Ballyhale Shamrocks won the championship after a 3–13 to 1–10 defeat of Muckalee/Ballyfoyle Rangers in the final replay. It was their third championship title overall and their third title in succession.