1980 Lafayette Leopards football team

The 1980 Lafayette Leopards football team was an American football team that represented Lafayette College as an independent during the 1980 NCAA Division I-AA football season.

In their tenth year under head coach Neil Putnam, the Leopards compiled a 3–7 record. Steve MacCorkle and Ed Rogulsky were the team captains.

Lafayette played its home games at Fisher Field on College Hill in Easton, Pennsylvania.