1980 Sam Houston State Bearkats football team

The 1980 Sam Houston State Bearkats football team represented Sam Houston State University as a member of the Lone Star Conference (LSC) during the 1980 NAIA Division I football season. Led by third-year head coach Melvin Brown, the Bearkats compiled an overall record of 3–7 with a mark of 2–5 in conference play, and finished sixth in the LSC.