1980 Stella Artois Championships – Singles

John McEnroe was the defending champion and won the singles title at the 1980 Queen's Club Championships tennis tournament defeating Kim Warwick in the final 6–3, 6–1.

Seeds

 * 1) 🇺🇸 John McEnroe (champion)
 * 2) 🇺🇸 Vitas Gerulaitis (semifinals)
 * 3) 🇺🇸 Harold Solomon (withdrew)
 * 4) 🇺🇸 Roscoe Tanner (quarterfinals)
 * 5)  Víctor Pecci (semifinals)
 * 6) 🇺🇸 Peter Fleming (first round)
 * 7) 🇺🇸 Pat DuPré (first round)
 * 8) 🇺🇸 Victor Amaya (second round)
 * 9) 🇺🇸 Stan Smith (quarterfinals)
 * 10) 🇺🇸 John Sadri (third round)
 * 11) 🇺🇸 Brian Teacher (second round)
 * 12) 🇺🇸 Tim Gullikson (second round)
 * 13) 🇺🇸 Brian Gottfried (third round)
 * 14) 🇲🇽 Raúl Ramírez (second round)
 * 15)  Johan Kriek (second round)
 * 16) 🇮🇳 Vijay Amritraj (quarterfinals)