1980 US Open – Men's singles

Defending champion John McEnroe defeated Björn Borg in the final, 7–6(7–4), 6–1, 6–7(5–7), 5–7, 6–4 to win the men's singles tennis title at the 1980 US Open. It was his second US Open singles title and second major singles title overall. The final is often ranked among the best matches in tennis history, and was central to the Borg–McEnroe rivalry. It was the first successful US Open men's singles title defense in the Open Era.

Seeds
The seeded players are listed below. John McEnroe is the champion; others show the round in which they were eliminated.


 * 1) 🇸🇪 Björn Borg (finalist)
 * 2) 🇺🇸 John McEnroe (champion)
 * 3) 🇺🇸 Jimmy Connors (semifinalist)
 * 4) 🇦🇷 Guillermo Vilas (fourth round)
 * 5) 🇺🇸 Vitas Gerulaitis (second round)
 * 6) 🇺🇸 Gene Mayer (first round)
 * 7) 🇺🇸 Harold Solomon (fourth round)
 * 8) 🇺🇸 Eddie Dibbs (second round)
 * 9) 🇺🇸 Peter Fleming (second round)
 * 10)  Ivan Lendl (quarterfinalist)
 * 11) 🇺🇸 Roscoe Tanner (quarterfinalist)
 * 12) 🇦🇷 José Luis Clerc (first round)
 * 13) 🇺🇸 Brian Gottfried (fourth round)
 * 14) 🇵🇱 Wojtek Fibak (quarterfinalist)
 * 15) 🇫🇷 Yannick Noah (fourth round)
 * 16) 🇺🇸 Victor Amaya (third round)

Key

 * Q = Qualifier
 * WC = Wild card
 * LL = Lucky loser
 * r = Retired