1981 Texas Southern Tigers football team

The 1981 Texas Southern Tigers football team represented Texas Southern University as a member of the Southwestern Athletic Conference (SWAC) during the 1981 NCAA Division I-AA football season. Led by first-year head coach Joe Redmond, the Tigers compiled an overall record of 4–6–1, with a mark of 2–5 in conference play, and finished sixth in the SWAC.