1981 Women's World Open Squash Championship

The 1981 Women's World Open Squash Championship was the women's edition of the 1981 World Open, which serves as the individual world championship for squash players. The event took place in Toronto in Canada during October 1981. Rhonda Thorne won the World Open title, defeating Vicki Cardwell in the final.

Seeds
• # 🇦🇺 Vicki Cardwell (née Hoffman) (final)

• # 🇦🇺 Rhonda Thorne (champion)

• # 🏴󠁧󠁢󠁥󠁮󠁧󠁿 Sue Cogswell (quarterfinals)

• # 🇦🇺 Margaret Zachariah (quarterfinals)

• # 🏴󠁧󠁢󠁥󠁮󠁧󠁿 Angela Smith (semifinals)

• # 🏴󠁧󠁢󠁥󠁮󠁧󠁿 Lisa Opie (semifinals)

• # 🇦🇺 Rae Anderson (third round)

• # 🇬🇬 Martine Le Moignan (quarterfinals)