1985 US Open – Women's singles

Hana Mandlíková defeated the two-time defending champion Martina Navratilova in the final, 7–6(7–3), 1–6, 7–6(7–2) to win the women's singles tennis title at the 1985 US Open. It was her third major singles title.

Seeds
• # 🇺🇸 Chris Evert (semifinals)

• # 🇺🇸 Martina Navratilova (final)

• # Hana Mandlíková (champion)

• # 🇺🇸 Pam Shriver (quarterfinals)

• # Claudia Kohde-Kilsch (quarterfinals)

• # 🇺🇸 Zina Garrison (quarterfinals)

• # Helena Suková (quarterfinals)

• # 🇧🇬 Manuela Maleeva (fourth round)

• # 🇺🇸 Kathy Rinaldi (first round)

• # 🇦🇷 Gabriela Sabatini (first round)

• # Steffi Graf (semifinals)

• # 🇦🇺 Wendy Turnbull (fourth round)

• # 🇸🇪 Catarina Lindqvist (fourth round)

• # 🇺🇸 Bonnie Gadusek (third round)

• # 🇨🇦 Carling Bassett (fourth round)

• # 🇭🇺 Andrea Temesvári (second round)