1988 Nicholls State Colonels football team

The 1988 Nicholls State Colonels football team represented Nicholls State University as an independent during the 1988 NCAA Division I-AA football season. Led by second-year head coach Phil Greco, the Colonels compiled a record of 7–4. Nicholls State played home games at John L. Guidry Stadium in Thibodaux, Louisiana.