1988 OTB Open – Women's singles

Camille Benjamin was the defending champion but lost in the semifinals to Terry Phelps.

Gretchen Magers won in the final 7–6, 6–4 against Phelps.

Seeds
A champion seed is indicated in bold text while text in italics indicates the round in which that seed was eliminated.


 * 1) 🇺🇸 Elly Hakami (quarterfinals)
 * 2) 🇺🇸 Gretchen Magers (champion)
 * 3) 🇺🇸 Wendy White (second round)
 * 4) 🇺🇸 Terry Phelps (final)
 * 5) 🇺🇸 Ann Henricksson (first round)
 * 6) 🇺🇸 Camille Benjamin (semifinals)
 * 7) 🇺🇸 Lisa Bonder (first round)
 * 8) 🇺🇸 Amy Frazier (first round)