1988 Volvo U.S. National Indoor – Singles

Stefan Edberg was the defending champion, but lost in the third round to Jim Grabb.

Andre Agassi won the title by defeating Mikael Pernfors 6–4, 6–4, 7–5 in the final.

Seeds
All seeds received a bye to the second round. • # 🇸🇪 Stefan Edberg (third round)

• # 🇪🇨 Andrés Gómez (quarterfinals)

• # 🇺🇸 David Pate (quarterfinals)

• # 🇺🇸 Eliot Teltscher (third round, withdrew)

• # 🇮🇱 Amos Mansdorf (quarterfinals)

• # 🇺🇸 Andre Agassi (champion)

• # 🇸🇪 Peter Lundgren (second round)

• # Christo van Rensburg (third round)

• # 🇸🇪 Mikael Pernfors (final)

• # 🇺🇸 Kevin Curren (semifinals)

• # 🇮🇳 Ramesh Krishnan (third round)

• # 🇺🇸 Paul Annacone (third round)

• # 🇳🇿 Kelly Evernden (second round)

• # 🇺🇸 Jim Pugh (third round)

• # 🇺🇸 Johan Kriek (third round)

• # 🇺🇸 Jay Berger (second round)